Dean looks over to Cas in the Impala from 9x06 "Heaven Can't Wait" right when he says "Cas, I can't let you do this." Center text reads "NOTHING HAUNTS US"

Dean looking at Cas in Purgatory in 15x09 "The Trap" right after telling Cas needed to tell him something and Cas told him he didn't have to. Center text reads "LIKE THE THINGS"

Dean looking at Cas, horrified, in 15x18 "Despair" saying "Cas" right after realizing Cas is in love with him and about to sacrifice himself. Center text reads "WE DON'T SAY"